Inhibition of Candida parapsilosis mitochondrial respiratory pathways enhances susceptibility to caspofungin.
نویسندگان
چکیده
Among the Candida species, Candida parapsilosis has a unique mitochondrial respiratory network. The addition of inhibitors of the respiratory pathways in three clinical isolates of C. parapsilosis with high (> or =2- microg/ml) MICs of caspofungin significantly (fivefold) decreased caspofungin MICs but did not change fluconazole MICs.
منابع مشابه
Elevated chitin content reduces the susceptibility of Candida species to caspofungin.
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 50 2 شماره
صفحات -
تاریخ انتشار 2006